Gulrajas The conjugate of any one of embodiments 2 to 55, wherein the Effector moiety is selected from the group comprising an Effector, Acceptor and -[Acceptor-Effector], wherein. It is within the present invention that such macrocclic of the further targeting moiety is shown by any embodiment of such further targeting moiety. The infrared spectra of the ligands and the complexes are indicated in Figure 2 and selected characteristic frequencies are indicated in Table 3. A titration curve of Phen, prepared in the absence of metal cations, is shown as curve I in Figure 1. Such effector can be attached to the compound either directly or through a connecting moiety.
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Jukazahn The conjugate of any one of embodiments 1 to 64, wherein the first targeting moiety and the second targeting moiety are targeting the same target molecule. In an embodiment and as preferably used herein, C3-C 8 cycloalkyl means each and individually any of cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl and cyclooctyl. Inhibition zone of ligands, complexes, salt, and commercial antibiotics against a Gram-positive S. Conventional amino acids, also referred to as natural amino acids are identified according to their standard, one-letter or three-letter codes, as set forth in Table 1. Additionally, it is thus possible to diagnose and treat, respectively, tumors expressing a target with low density, such as, for example copies of the target or less per tumor cell while said tumors express a second target with high density, such as, for example, more than copies of the second target per tumor cell. In this case usually specific reagents are used for activation of at least one component, for instance the carboxylic acid. Based on such general formula, the conjugate of the invention may be realized embodiments such as embodiments I to VII outlined in the following.