Gulrajas The conjugate of any one of embodiments 2 to 55, wherein the Effector moiety is selected from the group comprising an Effector, Acceptor and -[Acceptor-Effector], wherein. It is within the present invention that such macrocclic of the further targeting moiety is shown by any embodiment of such further targeting moiety. The infrared spectra of the ligands and the complexes are indicated in Figure 2 and selected characteristic frequencies are indicated in Table 3. A titration curve of Phen, prepared in the absence of metal cations, is shown as curve I in Figure 1. Such effector can be attached to the compound either directly or through a connecting moiety.

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Cited By This article is cited by 59 publications. Inorganic Chemistry , 58 11 , DOI: Inorganic Chemistry , 58 9 , Mark A. Lashley, Alexander S. Ivanov, Vyacheslav S. Bryantsev, Sheng Dai, and Robert D.

Inorganic Chemistry , 55 20 , Inorganic Chemistry , 53 20 , Celina Gwizdala, Prem N. Basa, John C. MacDonald, and Shawn C. Inorganic Chemistry , 52 15 , Ashley N. Carolan, Amy E. VanDerveer, Randolph P. Thummel, and Robert D. A Crystallographic, Fluorescence, and Thermodynamic Study.

Inorganic Chemistry , 51 5 , Danielle Merrill, James M. Inorganic Chemistry , 50 17 , Joanna M. Hamilton, Jason R. Whitehead, Neil J. Inorganic Chemistry , 50 8 , Hamilton, Michael J. Anhorn, Karen A. Oscarson, Joseph H. Reibenspies, and Robert D. Inorganic Chemistry , 50 7 , Chemistry of Materials , 22 14 , Bioconjugate Chemistry , 21 3 , Raymond T. Williams, Joseph H.

Reibenspies, Alvaro S. De Sousa and Robert D. A Crystallographic and Thermodynamic Study. Inorganic Chemistry , 48 17 , Neil J. Williams, Nolan E. Dean, Donald G. VanDerveer, Robert C. Luckay and Robert D. A Crystallographic, Fluorometric, and Thermodynamic Study. Inorganic Chemistry , 48 16 , Inorganic Chemistry , 48 10 , Inorganic Chemistry , 47 22 , Nolan E.

Dean, Robert D. Hancock, Christopher L. Cahill and Mark Frisch. Inorganic Chemistry , 47 6 , Gregory M. Cockrell,, Gang Zhang,, Donald G. VanDerveer,, Randolph P. Thummel, and, Robert D. Journal of the American Chemical Society , 4 , Dalton Transactions , DOI: On the preferences of five-membered chelate rings in coordination chemistry: insights from the Cambridge Structural Database and theoretical calculations.

Dalton Transactions , 48 17 , Daniel G. Ballance, Vyacheslav S. Bryantsev, Alexander S. Ivanov, Sheng Dai, Robert D. Complexation of lanthanides and other metal ions by the polypyridyl ligand quaterpyridine: Relation between metal ion size, chelate ring size, and complex stability. Inorganica Chimica Acta , , Seven and eight-coordinate Fe III complexes containing pre-organized ligand 1,phenanthroline-2,9-dicarboxylic acid: Solvent effects, supramolecular interactions and DFT calculations.


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Jukazahn The conjugate of any one of embodiments 1 to 64, wherein the first targeting moiety and the second targeting moiety are targeting the same target molecule. In an embodiment and as preferably used herein, C3-C 8 cycloalkyl means each and individually any of cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl and cyclooctyl. Inhibition zone of ligands, complexes, salt, and commercial antibiotics against a Gram-positive S. Conventional amino acids, also referred to as natural amino acids are identified according to their standard, one-letter or three-letter codes, as set forth in Table 1. Additionally, it is thus possible to diagnose and treat, respectively, tumors expressing a target with low density, such as, for example copies of the target or less per tumor cell while said tumors express a second target with high density, such as, for example, more than copies of the second target per tumor cell. In this case usually specific reagents are used for activation of at least one component, for instance the carboxylic acid. Based on such general formula, the conjugate of the invention may be realized embodiments such as embodiments I to VII outlined in the following.





1103A 33TG1 PDF


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